Взаємозв’язок серцево-судинної патології та захворювань тканин пародонта
Ключові слова:
захворювання тканин пародонта, серцево-судинна патологія, атеросклероз, інфекційний ендокардит, пародонтопатогенна мікрофлора
Анотація
У статті представлено огляд літератури, яка містить сучасні погляди на етіологію та патогенез запальних захворювань тканин пародонта, їх зв’язок із патологією серцево-судинної системи. Наведено сучасні дані про роль пародонтопатогенної мікрофлори в ініціації та розвитку серцево-судинних захворювань. Патогенетичною ланкою, що підсилює зв’язок між серцево-судинною патологією та захворюваннями тканин пародонта, є системна запальна реакція. Поєднаний перебіг соматичної та стоматологічної патології потребує від стоматологів і кардіологів спільних зусиль із профілактики загальних факторів ризику.
Посилання
1. Данилевский Н. Ф., Борисенко А. В. Заболевания па родонта. – К. : Здоров’я, 2000. – 464 с.
2. Мазур И. П., Харченко Н. Л. Микробиологический мониторинг транзиторной бактериемии у стоматологических больных // Дентальные технологии. – 2010. – № 1 (44). – С. 10–13.
3. Variations of Porphyromonasgingivalis fimbriae in relation to microbial pathogenesis / Amano A., Nakagawa I., Okahashi N. et al. // J Periodont Res. – 2004. – Vol. 39. – P. 136–42.
4. Detection of Transient Bacteraemia following Dental Extractions by 16S rDNA Pyrosequencing: A Pilot Study / Alfonso Benнtez-Pбez, Maximiliano Бlvarez, Pedro Belda-Ferre et al. // PLoS One. – 2013. – Vol. 8 (3). – e57782.
5. Silvestre FJ. Cardiovascular disease versus periodontal disease: Chronic systemic infection as a link / Alonso-Gonzбlez R., Pйrez-Hernбndez A., Silvestre-Rangil J. et al. // J ClinExpDent. – 2011. – Vol. 3. – e476.
6. Bacteremia following scaling and root planing: A clinico-microbiological study / Alka S. Waghmare, Priyanka B. Vhanmane, B. Savitha et al. // J Indian Soc Periodontol. – 2013 Nov-Dec. – Vol. 17 (6). – P. 725–730.
7. Dissemination of Periodontal Pathogens in the Bloodstream after Periodontal Procedures: A Systematic Revie / Anna Carolina Ratto Tempestini Horliana, Leandro Chambrone, Adriana Moura Foz et al. // PLoS One. – 2014. – Vol. 9 (5). – e98271.
8. Atherosclerotic cardiovascular diseases (ACVDs) are a leading cause of death and disability across the developed world and impose a vast burden on healthcare resources. This category of diseases includes / EFP & MS Media Service [www.perioworkshop.org] / MAY 2013
9. Amano A. Disruption of epithelial barrier and impairment of cellular function by Porphyromonas gingivalis // Front Biosci. – 2007. – Vol. 12. – P. 3965–74. [PubMed]
10. The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: a meta-analysis / Bahekar A. A., Singh S., Saha S. et al. // Am Heart J. – 2007. – Vol. 154. – P. 830–7.
11. Periodontitis in coronary heart disease patients: strong association between bleeding on probing and systemic biomarkers / Bokhari S. A. H., Khan A. A., Butt A. K. et al. // J ClinPeriodontol. – 2014. – Vol. 41. – P. 1048– 1054.
12. Periodontal diseases and cardiovascular events: Meta-analysis of observational studies / Blaizot A., Vergnes J. N., Nuwwareh S. et al. // Int Dent J. –2009. – Vol. 59. – P. 197–209. [PubMed]
13. Relationship between the oral cavity and cardiovascular diseases and metabolic syndrome / Carramolino-Cuйllar E., Tomбs I., Jimйnez-Soriano // Med Oral Patol Oral Cir Bucal. – 2014 May 1. – Vol. 19 (3). – e289–94.
14. Periodontitis may increase the risk of peripheral arterial disease / Chen Y. W. et al. // Eur J Vasc Endovasc Surg. – 2008. – Vol. 35. – P. 153–8.
15. Periodontitis and atherogenesis: causal association or simple coincidence / D’Aiuto F., Parkar M., Andreaou G. et al. // J Clin Periodontol. – 2004. – Vol. 31. – P. 402–411.
16. Evidence that periodontal treatment improves biomarkers and CVD outcomes / D’Aiuto F., Orlandi M., Gunsolley J. C. // J Clin Periodontol. – 2013. – Vol. 40. – P. 85–105.
17. Periodontitis and atherogenesis: causal association or simple coincidence / D’Aiuto F., Parkar M., Andreaou G. et al. // J Clin Periodontol. – 2004. – Vol. 31. – P. 402–11. [PubMed]
18. Serum antibodies to periodontal pathogens and markers of systemic inflammation / Dye B. A., Choudhary K., Shea S. et al. // J Clin Periodontol. – 2005. – Vol. 32. – P. 1189– 99. [PubMed]
19. De Nardin E. The role of inflammatory and immunological mediators in periodontitis and cardiovascular disease // Ann Periodontol. – 2001. – Vol. 6. – P. 30–40.
20. Incidence of bacteremia after chewing, tooth brushing and scaling in individuals with periodontal inflammation / Forner L., Larsen T., Kilian M. / J Clin Periodontol. –2006 Jun. – Vol. 33 (6). – P. 401–7.
21. Increased plasma levels of IL-6 in bacteremic periodontitis patients after scaling / Forner L., Nielsen C. H., Bendtzen K. et al. // J Clin Periodontol. – 2006. – Vol. 33. – P. 724–729.
22. The interaction of bacterial pathogens with platelets / Fitzgerald J. R., Foster T. J., Cox D. // Nat Rev Microbiol. – 2006. – Vol. 4. – P. 445–57. [PubMed]
23. Guidelines for the prevention of endocarditis: report of the Working Party of the British Society for Antimicrobial Chemotherapy / F. K. Gould1, T. S. J. Elliott, J. Foweraker et al. // Journal of Antimicrobial Chemotherapy. – 2006. – Vol. 57. – P. 1035–1042.
24. Georg A. Roth, Bernhard Moser. Infection with a periodontal pathogen increases mononuclear cell adhesion to human aortic endothelial cells / Atherosclerosis. – 2007. – Vol. 190. – P. 271–281;
25. Innate immune signaling and Porphyromonas gingivalis accelerated atherosclerosis / Gibson F. C., Yumoto H., Takahashi Y. et al. // J Dent Res. – 2006. – Vol. 85. – P. 106–121.
26. Systemic release of endotoxins induced by gentle mastication: association with periodontitis severity / Geerts S. O., Nys M., De M. P. et al. // J Periodontol. – 2002. – Vol. 73 (1). – P. 73–8.
27. Oral Inflammatory Diseases and Systemic Inflammation: Role of the Macrophage / Hatice Hasturk, Alpdogan Kantarci and Thomas E. Van Dyke // Front Immunol. – 2012. – Vol. 3. – P. 118.
28. Identification of periodontal pathogens in atheromatous plaques / Haraszthy V. I., Zambon J. J., Trevisan M. et al. // Periodontol. – 2007. – Vol. 1. – P. 1554–60. [PubMed]
29. Guidelines on prevention, diagnosis and treatment of infective endocarditis executive summary the task force on infective endocarditis of the European Society of Cardiology / Horstkotte D., Follath F., Gutschik E. et al. // Eur Heart J. – 2004. – Vol. 25. – P. 267–76.
30. Holt S. C., Ebersole J. L. Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia: the “red complex”, a prototype polybacterial pathogenic consortium in periodontitis // Periodontol. – 2000, 2005. – Vol. 38. – P. 72–122.
31. Porphyromonas gingivalis (Pg) a possible link between impaired oral health and acute myocardial infarction / Holmlund A., Hedin M., Pussinen P. J. et al. // Int J Cardiol. – 2009. – Vol. 148. – P. 148–53.
32. Role for periodontitis in the progression of lipid deposition in an animal model / Jain A., Batista E. L. et al. // Infect. Immun. – 2003. – Vol. 71, 6012–601810.1128/ IAI.71.10.6012-6018.2003
33. Meta-analysis of periodontal disease and risk of coronary heart disease and stroke / Janket S. J., Baird A. E., Chuang S. K. et al. // Oral Surg Oral Med Oral Pathol Oral Radiol Endod. – 2003. – Vol. 95. – P. 559–69. [PubMed]
34. Periodontal disease, tooth loss, and incidence of ischemic stroke / Joshipura K. J. et al. // Stroke. – 2003. – Vol. 34. – P. 47–52.
35. Bacteraemia following periodontal procedures / Kinane D. F., Riggio M. P., Walker K. F. et al. // J Clin Periodontol. – 2005 Jul. – Vol. 32 (7). – P. 708–13.
36. Bacteraemia following periodontal procedures / Kinane D. F., Riggio M. P., Walker K. F. et al. // J Clin Periodontol. – 2005. – Vol. 32 (7). – P. 708–13.
37. Role of periodontal bacteria in cardiovascular disease / Kuramitsu H. K., Qi M., Kang I. C. et al. // Ann periodontal. – 2001. – Vol. 6. – P. 41–7. [PubMed]
38. Oral infection with a periodontal pathogen accelerates early atherosclerosis in apolipoprotein E-null mice / Lalla E., Lamster I. B., Hofmann M. A. et al. // Arterioscler Thromb Vasc Biol. – 2003 Aug 1. – Vol. 23 (8). – P. 1405–11. Epub 2003 Jun 19.
39. Perio-dontal disease and atherosclerotic vascular disease: does the evidence support an independent asso-ciation: a scientific statement from the American Heart Association / Lockhart P. B., Bolger A. F., Papapanou P. N. et al. // Circulation. – 2012. – Vol. 125. – P. 2520–44.
40. Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase / Naito M., Sakai E., Shi Y. et al. // Mol. Microbiol. – 2006. – Vol. 59 (1). – P. 152–167.
41. Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease / Nakajima T., Honda T., Domon H. et al. // J Periodont Res. – 2010. – Vol. 45. – P. 116–122.
42. State of the science: chronic periodontitis and systemic health / Otomo-Corgel J., Pucher J. J., Rethman M. P. et al. // J Evid Based Dent Pract. – 2012. – Vol. 12 (3 Suppl). – P. 20–8.
43. A systematic review and meta – analyses on C – reactive protein in relation to periodontitis / Paraskevas S., Huizinga J. D., Loos B. G. // J Clin Periodontal. – 2008. – Vol. 35. – P. 277–90.
44. C-reactive protein associated with periodontitis in a Thai population / Pitiphat W., Savetsilp W., Wara-Aswapati N // J Clin Periodontol. – 2008. – Vol. 35. – P. 120–25. [PubMed]
45. The link between periodontal disease and cardiovascular disease: How far we have come in last two decades? / Prasad Dhadse, Deepti Gattani and Rohit Mishra // J Indian Soc Periodontol. – 2010 Jul-Sep. – Vol. 14 (3). – P. 148–154.
46. Ramsdale D. R., Turner-Stokes L. Advisory Group of the British Cardiac Society Clinical Practice Committee et al. Prophylaxis and treatment of infective endocarditis in adults: a concise guide // Clin Med. – 2004. – Vol. 4. – P. 545–50.
47. Reeves G. C-reactive protein // Aust Prescr. – 2007. – Vol. 30. – P. 74–76.
48. IgG sera levels against a subset of periodontopathogens and severity of disease in aggressive periodontitis patients: acrosssectional study of selected pocket sites / Saraiva L., Rebeis E. S., Martins E. S. et al. // J Clin Periodontol. – 2014. – Vol. 41. – P. 943–951.
49. C-reactive protein levels in patients with aggressive periodontitis / Salzberg T. N., Overstreet B. T., Rogers J. D. et al. // J Periodontol. – 2006. – Vol. 77. – P. 933–39. [PubMed]
50. Microbiological parameters associated with IL-1 gene polymorphisms in periodontitis patients / Socransky S. S., Haffajee A. D., Smith C. et al. // J Clin Periodontol. – 2000. – Vol. 27. – P. 8108.
51. Activation of human gingival epithelial cells by cell-surface components of blackpigmented bacteria: mentation of production of interleukin-8, granulocyte colony-stimulation factor and granulocyte-macrophage colony-stimulation factor and expression of intercellular adhesion molecule 1 / Sugiyama A., Uehara A., Matsushita K. et al. // Bact Pathogen. – 2002. – Vol. 51. – P. 27–33.
52. Porphyromonasgingivalis platelet aggregation activity: outer membrane vesicles are potent activators of murine platelets / Sharma A., Novak E. K., Sojar H. T. et al. // Oral Microbiol. Immunol. – 2000. – Vol. 15 (6). – P. 393–396.
53. Taguchi A. Association between Oral Health and the Risk of Lacunar Infarction in Japanese Adults / A. Taguchi, M. Miki, A. Muto [et al.] // Gerontology. – 2013. – Vol. 59, № 6. – P. 499–506.
54. Periodontal disease and risk of cerebrovascular disease: The First National Health and Nutrition Examination Survey and its follow-up study / Wu T. et al. // Arch Intern Med. – 2000. – Vol. 160. – P. 2749–55.
55. Wozakowska-Kaplon B. Oral health status and the occurrence and clinical course of myocardial infarction in hospital phase: A case-control study / B. Wozakowska-Kaplon, M. Wosowicz, I. Gorczyca-Michta et al. // Cardiol. J. – 2013. – Vol. 20, № 4. – P. 370–377.
56. Prevotella nigrescens and Porphyromonas gingivalis are associated with signs of carotid atherosclerosis in subjects with and without periodontitis / Yakob M., Sцder B., Meurman J. H. et al. // J Periodontal Res. – 2011. – Vol. 46. – P. 749–55.
57. Porphyromonas gingivalis induces myocarditis and/or myocardial infarction in mice and IL-17A is involved in pathogenesis of these diseases / Yuki Akamatsu, Toshiro Yamamoto et al. // Archives of oral biology. – 2011. – Vol. 56. – P. 1290–1298.
2. Мазур И. П., Харченко Н. Л. Микробиологический мониторинг транзиторной бактериемии у стоматологических больных // Дентальные технологии. – 2010. – № 1 (44). – С. 10–13.
3. Variations of Porphyromonasgingivalis fimbriae in relation to microbial pathogenesis / Amano A., Nakagawa I., Okahashi N. et al. // J Periodont Res. – 2004. – Vol. 39. – P. 136–42.
4. Detection of Transient Bacteraemia following Dental Extractions by 16S rDNA Pyrosequencing: A Pilot Study / Alfonso Benнtez-Pбez, Maximiliano Бlvarez, Pedro Belda-Ferre et al. // PLoS One. – 2013. – Vol. 8 (3). – e57782.
5. Silvestre FJ. Cardiovascular disease versus periodontal disease: Chronic systemic infection as a link / Alonso-Gonzбlez R., Pйrez-Hernбndez A., Silvestre-Rangil J. et al. // J ClinExpDent. – 2011. – Vol. 3. – e476.
6. Bacteremia following scaling and root planing: A clinico-microbiological study / Alka S. Waghmare, Priyanka B. Vhanmane, B. Savitha et al. // J Indian Soc Periodontol. – 2013 Nov-Dec. – Vol. 17 (6). – P. 725–730.
7. Dissemination of Periodontal Pathogens in the Bloodstream after Periodontal Procedures: A Systematic Revie / Anna Carolina Ratto Tempestini Horliana, Leandro Chambrone, Adriana Moura Foz et al. // PLoS One. – 2014. – Vol. 9 (5). – e98271.
8. Atherosclerotic cardiovascular diseases (ACVDs) are a leading cause of death and disability across the developed world and impose a vast burden on healthcare resources. This category of diseases includes / EFP & MS Media Service [www.perioworkshop.org] / MAY 2013
9. Amano A. Disruption of epithelial barrier and impairment of cellular function by Porphyromonas gingivalis // Front Biosci. – 2007. – Vol. 12. – P. 3965–74. [PubMed]
10. The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: a meta-analysis / Bahekar A. A., Singh S., Saha S. et al. // Am Heart J. – 2007. – Vol. 154. – P. 830–7.
11. Periodontitis in coronary heart disease patients: strong association between bleeding on probing and systemic biomarkers / Bokhari S. A. H., Khan A. A., Butt A. K. et al. // J ClinPeriodontol. – 2014. – Vol. 41. – P. 1048– 1054.
12. Periodontal diseases and cardiovascular events: Meta-analysis of observational studies / Blaizot A., Vergnes J. N., Nuwwareh S. et al. // Int Dent J. –2009. – Vol. 59. – P. 197–209. [PubMed]
13. Relationship between the oral cavity and cardiovascular diseases and metabolic syndrome / Carramolino-Cuйllar E., Tomбs I., Jimйnez-Soriano // Med Oral Patol Oral Cir Bucal. – 2014 May 1. – Vol. 19 (3). – e289–94.
14. Periodontitis may increase the risk of peripheral arterial disease / Chen Y. W. et al. // Eur J Vasc Endovasc Surg. – 2008. – Vol. 35. – P. 153–8.
15. Periodontitis and atherogenesis: causal association or simple coincidence / D’Aiuto F., Parkar M., Andreaou G. et al. // J Clin Periodontol. – 2004. – Vol. 31. – P. 402–411.
16. Evidence that periodontal treatment improves biomarkers and CVD outcomes / D’Aiuto F., Orlandi M., Gunsolley J. C. // J Clin Periodontol. – 2013. – Vol. 40. – P. 85–105.
17. Periodontitis and atherogenesis: causal association or simple coincidence / D’Aiuto F., Parkar M., Andreaou G. et al. // J Clin Periodontol. – 2004. – Vol. 31. – P. 402–11. [PubMed]
18. Serum antibodies to periodontal pathogens and markers of systemic inflammation / Dye B. A., Choudhary K., Shea S. et al. // J Clin Periodontol. – 2005. – Vol. 32. – P. 1189– 99. [PubMed]
19. De Nardin E. The role of inflammatory and immunological mediators in periodontitis and cardiovascular disease // Ann Periodontol. – 2001. – Vol. 6. – P. 30–40.
20. Incidence of bacteremia after chewing, tooth brushing and scaling in individuals with periodontal inflammation / Forner L., Larsen T., Kilian M. / J Clin Periodontol. –2006 Jun. – Vol. 33 (6). – P. 401–7.
21. Increased plasma levels of IL-6 in bacteremic periodontitis patients after scaling / Forner L., Nielsen C. H., Bendtzen K. et al. // J Clin Periodontol. – 2006. – Vol. 33. – P. 724–729.
22. The interaction of bacterial pathogens with platelets / Fitzgerald J. R., Foster T. J., Cox D. // Nat Rev Microbiol. – 2006. – Vol. 4. – P. 445–57. [PubMed]
23. Guidelines for the prevention of endocarditis: report of the Working Party of the British Society for Antimicrobial Chemotherapy / F. K. Gould1, T. S. J. Elliott, J. Foweraker et al. // Journal of Antimicrobial Chemotherapy. – 2006. – Vol. 57. – P. 1035–1042.
24. Georg A. Roth, Bernhard Moser. Infection with a periodontal pathogen increases mononuclear cell adhesion to human aortic endothelial cells / Atherosclerosis. – 2007. – Vol. 190. – P. 271–281;
25. Innate immune signaling and Porphyromonas gingivalis accelerated atherosclerosis / Gibson F. C., Yumoto H., Takahashi Y. et al. // J Dent Res. – 2006. – Vol. 85. – P. 106–121.
26. Systemic release of endotoxins induced by gentle mastication: association with periodontitis severity / Geerts S. O., Nys M., De M. P. et al. // J Periodontol. – 2002. – Vol. 73 (1). – P. 73–8.
27. Oral Inflammatory Diseases and Systemic Inflammation: Role of the Macrophage / Hatice Hasturk, Alpdogan Kantarci and Thomas E. Van Dyke // Front Immunol. – 2012. – Vol. 3. – P. 118.
28. Identification of periodontal pathogens in atheromatous plaques / Haraszthy V. I., Zambon J. J., Trevisan M. et al. // Periodontol. – 2007. – Vol. 1. – P. 1554–60. [PubMed]
29. Guidelines on prevention, diagnosis and treatment of infective endocarditis executive summary the task force on infective endocarditis of the European Society of Cardiology / Horstkotte D., Follath F., Gutschik E. et al. // Eur Heart J. – 2004. – Vol. 25. – P. 267–76.
30. Holt S. C., Ebersole J. L. Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia: the “red complex”, a prototype polybacterial pathogenic consortium in periodontitis // Periodontol. – 2000, 2005. – Vol. 38. – P. 72–122.
31. Porphyromonas gingivalis (Pg) a possible link between impaired oral health and acute myocardial infarction / Holmlund A., Hedin M., Pussinen P. J. et al. // Int J Cardiol. – 2009. – Vol. 148. – P. 148–53.
32. Role for periodontitis in the progression of lipid deposition in an animal model / Jain A., Batista E. L. et al. // Infect. Immun. – 2003. – Vol. 71, 6012–601810.1128/ IAI.71.10.6012-6018.2003
33. Meta-analysis of periodontal disease and risk of coronary heart disease and stroke / Janket S. J., Baird A. E., Chuang S. K. et al. // Oral Surg Oral Med Oral Pathol Oral Radiol Endod. – 2003. – Vol. 95. – P. 559–69. [PubMed]
34. Periodontal disease, tooth loss, and incidence of ischemic stroke / Joshipura K. J. et al. // Stroke. – 2003. – Vol. 34. – P. 47–52.
35. Bacteraemia following periodontal procedures / Kinane D. F., Riggio M. P., Walker K. F. et al. // J Clin Periodontol. – 2005 Jul. – Vol. 32 (7). – P. 708–13.
36. Bacteraemia following periodontal procedures / Kinane D. F., Riggio M. P., Walker K. F. et al. // J Clin Periodontol. – 2005. – Vol. 32 (7). – P. 708–13.
37. Role of periodontal bacteria in cardiovascular disease / Kuramitsu H. K., Qi M., Kang I. C. et al. // Ann periodontal. – 2001. – Vol. 6. – P. 41–7. [PubMed]
38. Oral infection with a periodontal pathogen accelerates early atherosclerosis in apolipoprotein E-null mice / Lalla E., Lamster I. B., Hofmann M. A. et al. // Arterioscler Thromb Vasc Biol. – 2003 Aug 1. – Vol. 23 (8). – P. 1405–11. Epub 2003 Jun 19.
39. Perio-dontal disease and atherosclerotic vascular disease: does the evidence support an independent asso-ciation: a scientific statement from the American Heart Association / Lockhart P. B., Bolger A. F., Papapanou P. N. et al. // Circulation. – 2012. – Vol. 125. – P. 2520–44.
40. Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase / Naito M., Sakai E., Shi Y. et al. // Mol. Microbiol. – 2006. – Vol. 59 (1). – P. 152–167.
41. Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease / Nakajima T., Honda T., Domon H. et al. // J Periodont Res. – 2010. – Vol. 45. – P. 116–122.
42. State of the science: chronic periodontitis and systemic health / Otomo-Corgel J., Pucher J. J., Rethman M. P. et al. // J Evid Based Dent Pract. – 2012. – Vol. 12 (3 Suppl). – P. 20–8.
43. A systematic review and meta – analyses on C – reactive protein in relation to periodontitis / Paraskevas S., Huizinga J. D., Loos B. G. // J Clin Periodontal. – 2008. – Vol. 35. – P. 277–90.
44. C-reactive protein associated with periodontitis in a Thai population / Pitiphat W., Savetsilp W., Wara-Aswapati N // J Clin Periodontol. – 2008. – Vol. 35. – P. 120–25. [PubMed]
45. The link between periodontal disease and cardiovascular disease: How far we have come in last two decades? / Prasad Dhadse, Deepti Gattani and Rohit Mishra // J Indian Soc Periodontol. – 2010 Jul-Sep. – Vol. 14 (3). – P. 148–154.
46. Ramsdale D. R., Turner-Stokes L. Advisory Group of the British Cardiac Society Clinical Practice Committee et al. Prophylaxis and treatment of infective endocarditis in adults: a concise guide // Clin Med. – 2004. – Vol. 4. – P. 545–50.
47. Reeves G. C-reactive protein // Aust Prescr. – 2007. – Vol. 30. – P. 74–76.
48. IgG sera levels against a subset of periodontopathogens and severity of disease in aggressive periodontitis patients: acrosssectional study of selected pocket sites / Saraiva L., Rebeis E. S., Martins E. S. et al. // J Clin Periodontol. – 2014. – Vol. 41. – P. 943–951.
49. C-reactive protein levels in patients with aggressive periodontitis / Salzberg T. N., Overstreet B. T., Rogers J. D. et al. // J Periodontol. – 2006. – Vol. 77. – P. 933–39. [PubMed]
50. Microbiological parameters associated with IL-1 gene polymorphisms in periodontitis patients / Socransky S. S., Haffajee A. D., Smith C. et al. // J Clin Periodontol. – 2000. – Vol. 27. – P. 8108.
51. Activation of human gingival epithelial cells by cell-surface components of blackpigmented bacteria: mentation of production of interleukin-8, granulocyte colony-stimulation factor and granulocyte-macrophage colony-stimulation factor and expression of intercellular adhesion molecule 1 / Sugiyama A., Uehara A., Matsushita K. et al. // Bact Pathogen. – 2002. – Vol. 51. – P. 27–33.
52. Porphyromonasgingivalis platelet aggregation activity: outer membrane vesicles are potent activators of murine platelets / Sharma A., Novak E. K., Sojar H. T. et al. // Oral Microbiol. Immunol. – 2000. – Vol. 15 (6). – P. 393–396.
53. Taguchi A. Association between Oral Health and the Risk of Lacunar Infarction in Japanese Adults / A. Taguchi, M. Miki, A. Muto [et al.] // Gerontology. – 2013. – Vol. 59, № 6. – P. 499–506.
54. Periodontal disease and risk of cerebrovascular disease: The First National Health and Nutrition Examination Survey and its follow-up study / Wu T. et al. // Arch Intern Med. – 2000. – Vol. 160. – P. 2749–55.
55. Wozakowska-Kaplon B. Oral health status and the occurrence and clinical course of myocardial infarction in hospital phase: A case-control study / B. Wozakowska-Kaplon, M. Wosowicz, I. Gorczyca-Michta et al. // Cardiol. J. – 2013. – Vol. 20, № 4. – P. 370–377.
56. Prevotella nigrescens and Porphyromonas gingivalis are associated with signs of carotid atherosclerosis in subjects with and without periodontitis / Yakob M., Sцder B., Meurman J. H. et al. // J Periodontal Res. – 2011. – Vol. 46. – P. 749–55.
57. Porphyromonas gingivalis induces myocarditis and/or myocardial infarction in mice and IL-17A is involved in pathogenesis of these diseases / Yuki Akamatsu, Toshiro Yamamoto et al. // Archives of oral biology. – 2011. – Vol. 56. – P. 1290–1298.
Опубліковано
2018-03-12
Як цитувати
1.
Вітовський РМ, Мазур ІП, Слободяник МВ, Мартищенко ІВ. Взаємозв’язок серцево-судинної патології та захворювань тканин пародонта. ujcvs [інтернет]. 12, Березень 2018 [цит. за 25, Травень 2025];(1 (30):72-8. доступний у: http://cvs.org.ua/index.php/ujcvs/article/view/103
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ЗАГАЛЬНІ ПИТАННЯ ЛІКУВАННЯ ПАЦІЄНТІВ ІЗ СЕРЦЕВО-СУДИННОЮ ПАТОЛОГІЄЮ
