Comparative analysis of Treadmill Walking with different occlusion pressure on aerobic capacity and muscle strength among Sedentary Collegiates- A Randomized Controlled Trial
Abstract
Background. Sedentary lifestyles among college students pose a significant public health challenge, contributing to diminished aerobic capacity and muscle strength. Blood Flow Restriction training (BFRT) has emerged as an effective method to enhance physiological adaptations with low mechanical stress.
Aim. This study evaluates the comparative effects of treadmill walking under varying occlusion pressures on aerobic capacity and knee extensors strength in sedentary collegiate.
Materials and Methods. Thirty sedentary college students (aged 18-25 years) were randomized into three groups: Group A (low-pressure BFRT at 40 % limb occlusion), Group B (high-pressure BFRT at 60 % limb occlusion), and Group C (control, no occlusion). Participants underwent supervised treadmill walking for 20 minutes, three times per week over four weeks. Outcomes measured pre- and post-intervention included VO₂ max (aerobic capacity) and quadriceps strength. Statistical analysis was performed using SPSS v25.0 with significance set at p<0.05. A one-way ANOVA was employed to compare differences between groups at baseline and post-intervention. Paired t-tests were used for within-group comparisons.
Results. Significant improvements were observed in group A&B. Although Group B demonstrated the highest increase in VO₂ max (18 %) and muscle strength (22 %), followed by Group A (13 % and 16 %, respectively), while Group C showed minimal gains (6 % VO₂ max, 8 % strength) with no adverse events occurred in any group.
Conclusions. Treadmill walking with BFRT especially at higher occlusion pressures is an effective, safe, and time-efficient intervention to enhance aerobic capacity and knee extensors strength in sedentary young adults. These findings support the integration of individualized BFRT protocols in fitness and rehabilitation settings to counteract inactivity-related deconditioning.
References
- Beak HJ, Park W, Yang JH, Kim J. Effect of low-intensity aerobic training combined with blood flow restriction on body composition, physical fitness, and vascular responses in recreational runners. Healthcare. 2022;10(9):1789. https://doi.org/10.3390/healthcare10091789
- Chen L, Zhang Z, Qu W, Huang W, Sun J, Duan X, Li D. Effects of blood flow restriction moderate intensity interval training on aerobic and anaerobic capabilities and lower extremity performance in male college basketball players. BMC Sports Sci Med Rehabil. 2025;17:44. https://doi.org/10.1186/s13102-025-01100-x
- Zhang Z, Gao X, Gao L. Effects of blood flow restriction training on aerobic capacity and performance in endurance athletes: a systematic review and meta-analysis. BMC Sports Sci Med Rehabil. 2025;17:160. https://doi.org/10.1186/s13102-025-01194-3
- Dong K, Tang J, Xu C, et al. The effects of blood flow restriction combined with endurance training on athletes' aerobic capacity, lower limb muscle strength, anaerobic power and sports performance: a meta-analysis. BMC Sports Sci Med Rehabil. 2025;17:24. https://doi.org/10.1186/s13102-025-01072-y
- Barbosa BCR, Menezes-Júnior LAA, de Paula W, et al. Sedentary behavior and mental health of university students during COVID-19: cross-sectional study. BMC Public Health. 2024;24:1860. https://doi.org/10.1186/s12889-024-19345-5
- Kuzik N, da Costa BGG, Hwang Y, et al. School-related sedentary behaviours and indicators of health and wellbeing among children and youth: a systematic review. Int J Behav Nutr Phys Act. 2022;19:40. https://doi.org/10.1186/s12966-022-01258-4
- Menon AR, Bharath KR, Thadathil T. Inherent sedentary behavior in college students in Kerala. J Community Health Manag. 2024;11(2):102-107. https://doi.org/10.18231/j.jchm.2024.017
- Jiang X, Che T. Effects of aerobic exercise combined with blood flow restriction on physical fitness and mental health of high school students. Front Psychol. 2025;16:1654855. https://doi.org/10.3389/fpsyg.2025.1654855
- Thompson KMA, Gamble ASD, Kontro H, Lee JB, Burr JF. Low- and high-volume blood-flow restriction treadmill walking improves maximal aerobic capacity. Scand J Med Sci Sports. 2024;e14534. https://doi.org/10.1111/sms.14534
- Herda AA, Cleary CJ, Young D, et al. Blood flow restriction during walking does not impact body composition or performance in highly trained runners. J Funct Morphol Kinesiol. 2024;9(2):74. https://doi.org/10.3390/jfmk9020074
- Govindasamy K, Suresh C, Kaur D, et al. Differential effects of a 12-week aerobic exercise program among obese adults: RCT. Health Sport Rehabil. 2023;9(2):230. https://doi.org/10.34142/HSR.2023.09.02.01
- Shah JN, Ketkar A. Physical activity and sedentary behaviour in computer science students: cross-sectional study. Int J Community Med Public Health. 2020. https://doi.org/10.18203/2394-6040.ijcmph20203406
- Jha JP, Chaudhary HP, Pun DB, et al. Physical activity, sleep pattern and screen use in Nepal health-science students: cross-sectional study. medRxiv. 2025. https://doi.org/10.1101/2025.02.23.25322750v1
- Mitra S, Mitra M, Nandi P, et al. Yogistic efficacy on cardiopulmonary and musculoskeletal function in female college students. Work. 2024;79(1):230200. https://doi.org/10.3233/WOR230200
- Xiong F, Wang L, Xiang Y, et al. Effects of blood flow restriction exercise on endurance and aerobic capacity: systematic review. 2023. https://doi.org/10.21203/rs.3.rs2545926/v1
- Oliveira PC, Lan C, et al. Effects of blood flow restriction aerobic exercise on body composition and cardiovascular function: narrative review. Int J Mol Sci. 2024;25(17):9274. https://doi.org/10.3390/ijms25179274
- Wang S, Tang J, Liu S, et al. Repeated sprint training effects on aerobic/anaerobic power in rugby players. Front Physiol. 2025;16:1620197. https://doi.org/10.3389/fphys.2025.1620197


