Comparison of the Effectiveness of Radiofrequency Ablation Aortorenal Ganglia in Patients with Hypertension, Depending on the State of the Autonomic Nervous System

  • B. V. Batsak National M. M. Amosov Institute of Cardiovascular Surgery National Academy of Medical Sciences of Ukraine
  • B. N. Gumenyuk National M. M. Amosov Institute of Cardiovascular Surgery National Academy of Medical Sciences of Ukraine
  • E. M. Trembovetskaya National M. M. Amosov Institute of Cardiovascular Surgery National Academy of Medical Sciences of Ukraine
  • V. V. Lazorishinetz National M. M. Amosov Institute of Cardiovascular Surgery National Academy of Medical Sciences of Ukraine
Keywords: arterial hypertension, radiofrequency ablation, sympathetic denervation

Abstract

The aim of this study was to explore the efficacy of radiofrequency ablation of renal paravertebral sympathetic ganglia to reduce blood pressure in patients with essential hypertension in hypertensive patients, depending on the state of the autonomic nervous system.

36 patients with arterial hypertension underwent radiofrequency ablation of prevertebral sympathetic ganglia. The hypersympathetic state was in 24 patients.

It was found more significant reduction in systolic blood pressure (in the group average of 29,3±7,5 mm Hg) in patients with hypersympathetic state compared with patients without hypersympathetic state respectively 15,3±4,5 mm Hg, 12 months after ablation.

Our result indicate that the radiofrequency ablation of the sympathetic preverberal ganglia significantly lowering blood pressure in patients with chronic activation of sympathetic nervous system.

References

1. Newcombe C., Shucksmith H., Suffern W. Sympathectomy for Hypertension // Br Med J. – 1959. – Vol. 1 (5115). – P. 142–144.

2. Smithwick R., Thompson J. Splanchnicectomy for essential hypertension; resultsin 1,266 cases // J Am Med Assoc. – 1953. – Vol. 152 (16). – P. 1501–1504.

3. Krum H., Schlaich M., Whitbourn R. et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study //Lancet. – 2009. – Vol. 373. – P. 1275–81.

4. F. E. M. Fadl Elmula et al. Meta-analysis of randomized controlled trials of renal denervation in treatment-resistant hypertension. – Blood Pressure, 2015. – P. 263–274.

5. Sakakura et al. Anatomy of Human Renal Nerves // JACC. – 2014. – Vol. 64, № 7. – P. 635–43.
Published
2016-05-16
How to Cite
1.
Batsak BV, Gumenyuk BN, Trembovetskaya EM, Lazorishinetz VV. Comparison of the Effectiveness of Radiofrequency Ablation Aortorenal Ganglia in Patients with Hypertension, Depending on the State of the Autonomic Nervous System. ujcvs [Internet]. 2016May16 [cited 2024Dec.22];(1 (24):115-8. Available from: http://cvs.org.ua/index.php/ujcvs/article/view/286
Section
OTHER DISEASES OF THE CARDIOVASCULAR SYSTEM

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