Thrombolysis choise for pulmonary embolism treatment

  • A. S. Nikonenko Zaporozhye Medical Academy of Postgraduate Education; Zaporozhye State Medical University
  • A. A. Nikonenko Zaporozhye State Medical University
  • S. A. Matvieiev Zaporozhye State Medical University
  • V. V. Osaulenko Zaporozhye Medical Academy of Postgraduate Education
  • S. Y. Nakonechniy Zaporozhye Medical Academy of Postgraduate Education
Keywords: thrombosis, angiopulmonography, multislice computed tomography of the chest, thrombolysis

Abstract

Pulmonary embolism is a complex clinical problem, which is often cause of acute heart failure, death and disability of patients.

An aim of the study was to analyze the results of the various methods of treatment of PE to evaluate the effectiveness of therapy.

The results of treatment of 349 patients with pulmonary embolism, whom using thrombolysis and anticoagulation therapy were analyzed. There was found high efficiency of thrombolytic therapy for massive and submassive pulmonary embolism.

References

1. Guidelines on the diagnosis and management of acute pulmonary embolism. The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) / Torbicki A., Perrier A., Konstantinides S. et al. // European Heart Journal. – 2008. – Vol. 29 (18). – Р. 2276–2315.

2. Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonaryperfusion / Goldhaber S. Z., Haire W. D., Feldstein M. L. et al. // Lancet. – 1993. – Vol. 341 (8844). – Р. 507–511.

3. 3. Role of thrombolytics in the management of sub-massive pulmonary embolism / Nazir U., Berger P. A., Pitts L. R., Satterwhite L. G., et al. // OA Critical Care. – 2014. – Feb 22. – Vol. 2 (1).

4. 4. Daley, M. J., Murthy, M. S., & Peterson, E. J. Bleeding risk with systemic thrombolytic therapy for pulmonary embolism: scope of the problem / Daley, M. J. // Therapeutic Advancesin Drug Safety. – 2015. – Vol. 6 (2). – Р. 57–66.
Published
2016-09-12
How to Cite
Nikonenko, A. S., Nikonenko, A. A., Matvieiev, S. A., Osaulenko, V. V., & Nakonechniy, S. Y. (2016). Thrombolysis choise for pulmonary embolism treatment. Ukrainian Journal of Cardiovascular Surgery, (2 (25), 90-92. Retrieved from http://cvs.org.ua/index.php/ujcvs/article/view/244
Section
OTHER DISEASES OF THE CARDIOVASCULAR SYSTEM