Case report of hemolytic anemia after mitral valve repair

  • L. V. Pidhaina Ukrainian Children’s Cardiac Center (Kyiv)
  • S. I. Mohnatiy Ukrainian Children’s Cardiac Center (Kyiv)
  • O. D. Bablyak Ukrainian Children’s Cardiac Center (Kyiv)
  • O. M. Dovgan Ukrainian Children’s Cardiac Center (Kyiv)
  • N. M. Rudenko Ukrainian Children’s Cardiac Center (Kyiv)
Keywords: hemolytic anemia, mitral valve repair, regurgitant jet, heart failure


Hemolytic anemia after mitral valve repair is still an underestimated complication because it is a rare condition and there are few described case reports in the literature. The mechanism responsible for hemolysis most commonly involves a regurgitant jet and it appears to be independent of its severity as assessed by echocardiography. Patients may experience severe symptoms with only moderate regurgitant jets.

We present a case of a 66-year-old male who developed severe hemolytic anemia and decompensated heart failure. The aortic valve’ prothesis function was normal.There was a moderate mitral valve regurgitation jet, but it was not considered severe enough to explain such hemolysis. After exclusion of other causes of hemolytic anemia and the lack of clinical and laboratory improvement, the patient underwent mitral valve re-repair. Anemia and heart failure symptoms gradually resolved after surgery.

Cardiologists, cardiosurgeons, general practitioners should consider an availability of developmentof hemolytic anemia avter mitral valve repair. Transesophageal echocardiography is an important tool for diagnosis of the problem.


1. Askin Gungunes. Do All Hemolytic Anemias That Occur After Mitral Valve Repair Require Surgical // Clin. Cardiol. – 2010. – Vol. 33, 12, E 76–E78.

2. Buu-Khanh Lam et al. Hemolysis After Mitral Valve Repair: Mechanisms and Treatment // Ann Thorac Surg. – 2004. – Vol. 77. – P. 191–5.

3. Cardoso, Garcia et al. Hemolytic anemia after mitral valve repair: a case report // BMC Research Notes. – 2013. – Vol. 6. – P. 165.

4. Cheng et al. Mechanisms of Hemolysis After Mitral Valve Repair: Assessment by Serial Echocardiography // JACC. – 1998. – Vol. 32, No. 3. – P. 717–23.

5. Georges AbouRjaili et al. Hemolytic anemia following mitral valve repair: A case presentation and literature review // Clin Cardiol. – 2012. – Vol. 17 (4). – P. 248–250.

6. Parker Ward et al. Hemolysis After Mitral Valve Repair // Circulation. – 2000. – Vol. 101. – P. 695–696.

7. Sarinya Puwanant et al. Hemolytic Anemia after Mitral Valve Repair // Engl j med. – 2012. – P. 367.
How to Cite
Pidhaina, L. V., Mohnatiy, S. I., Bablyak, O. D., Dovgan, O. M., & Rudenko, N. M. (2016). Case report of hemolytic anemia after mitral valve repair. Ukrainian Journal of Cardiovascular Surgery, (3 (26), 115-117. Retrieved from

Most read articles by the same author(s)