Influence of left ventricular diastolic dysfunction on results after reconstruction mitral valve surgery in patients with mitral regurgitation

  • O. F. Luchynets National M.M. Amosov Institute of Cardiovascular Surgery National Academy of Medical Sciences of Ukraine
Keywords: left ventricular systolic dysfunction, mitral regurgitation, comparative analysis

Abstract

This research was based on the data of 218 patients with mitral valve regurgitation, who received surgical treatment at National M.M. Amosov Institute of Cardiovascular Surgery National Academy of Medical Sciences of Ukraine from 01.01.2010 to 01.01.2015 years. The average age of patients was 52, 8 ± 13,0 years (16,0-78,0).In postoperative period signs of heart failure (HF) were diagnosed in 43 (19.7%) cases. Hospital mortality was 2.3%. Comparative analysis of clinical data between subgroups of hemodynamically stable patients and patients HF and in postoperative period was performed. Left ventricular(LV) systolic dysfunction in patients with mitral regurgitation(MR) determined the risk of HF in the early postoperative period and adverse outcome. In patients with MR initial decrease of left ventricular ejection fraction(LVEF) to 50% was associated with adverse surgical treatment outcome.

References

1. Tribouilloy C., Grigioni F., Avierinos J. F., et al. Survival implication of left ventricular end- systolic diameter in mitral regurgitation due to flail leaflets a long-term follow-u pmulticenter study // J AmCollCardiol. – 2009 Nov., 17. – Vol. 54 (21). – P. 1961-8.

2. Zoghbi W. A., Enriquez-Sarano M., Foster E., et al. Recommendations fo revaluation of these verity o fnativevalvular regurgitation with two-dimensional and Doppler echocardiography. J AmSocEchocardiogr. – 2003Jul. – Vol. 16 (7). – P. 777-802.

3. Enriquez-Sarano M., Avierinos J. F., et al. Quantitative determinants of the outcome of asymptomatic mitral regurgitation // N Engl J Med. – 2005 Mar 3. – Vol. 352 (9). – P. 875-83.

4. Audrey H. Wu, MD, MPH *; Keith D. Aaronson, MD, MS*; Steven F. Bolling, MD, FACC, et al. Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction // J AmCollCardiol. – 2005. – Vol. 45 (3). – P. 381-387.

5. Flemming M. A., Oral H., Rothman E. D.,et al. Echocardiographic markers for mitral valve surgery to preserve left ventricular performance in mitral regurgitation // AmHeart J. – Sep. 2000 – Vol. 1403). – P. 476-82.

6. MauriceEnriquez-Sarano, Rakesh M. Suri, etal. Early and long-term analysis of patients with organic mitral regurgitation. The Journal of Thoracic and Cardiovascular Surgery, 2015; 150 (1): 50DOI: 10.1016 / j.jtcvs.2015.04.009

7. PeymanNaji, MD; Brian P. Griffin, MD et al. Importance of exercise capacity in predicting outcomes and determining optimal timing of surgery in significant primary mitral regurgitation. J AmHeartAssoc. 2014; 3: e001010 doi: 10.1161 / JAHA.114.001010

8. Kang D.-H., Park S.-J., Sun B.J., et al; Early surgery versus conventional treatment for asymptomatic severe mitral regurgitation: a propensity analysis. J AmCollCardiol. 2014; 63: 2398-2407.

9. Vahanian A., Alfieri O., Andreotti F., etal; Guidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). EurHeart J. 2012; 33: 2451-2496.

10. JeffreyS. Borer, MD. Early Surgery or Watchful Waiting for Asymptomatic Severe Degenerative Mitral Regurgitation. JamCollCardiol. in 2014; 63 (22): 2408-2410. doi: 10.1016 / j.jacc.2014.03.003.
Published
2016-09-12
How to Cite
Luchynets, O. F. (2016). Influence of left ventricular diastolic dysfunction on results after reconstruction mitral valve surgery in patients with mitral regurgitation. Ukrainian Journal of Cardiovascular Surgery, (2 (25), 32-35. Retrieved from https://cvs.org.ua/index.php/ujcvs/article/view/227
Section
ACQUIRED HEART DISEASES