A Case of Duodenal Bleeding in a One-Year-Old Child in the Early Postoperative Period after the Surgical Correction of Congenital Heart Defect

Keywords: stress ulcer, young children, intensive care, gastroduodenal complications prophylaxis, proton pump inhibitors, case report

Abstract

Background. Gastrointestinal bleeding in children is a rather rare pathology. This especially applies to the bleeding in the postoperative period after surgical interventions that are not related to the pathology of the gastrointestinal tract. As a result, clinicians are not alert to the occurrence of such complications, which, in turn, can lead to late diagnosis and delay in the treatment of bleeding.

Case report. We present a clinical case of duodenal bleeding in a one-year-old child in the early postoperative period after radical repair of ventricular septal defect by patching the defect. Laboratory parameters on admission: hemoglobin 120 g/L, red blood cells 4.37×1012/L. On the first postoperative day, hemoglobin was 103 g/L, hematocrit was 33%. On the 5th day after the operation, the boy had a currant jelly stool. Hemostatic therapy was provided: transfusion of fresh frozen plasma at a dose of 10 mL/kg, single administration of tranexamic acid at a dose of 10 mg/kg. The bleeding was stopped. After hemostatic therapy, hemoglobin was 105 g/L, hematocrit was 31%. Within 24 hours, fibrogastroduode-noscopy was performed which revealed an ulcer of the duodenal bulb covered with fibrin. The boy was consulted by gastroenterologist. Pathogenetic therapy was prescribed: proton pump inhibitors, antacids, enveloping drugs. The child was discharged home in a satisfactory condition on the 15th day after the operation under the supervision of a district pediatrician, cardiologist, and gastroenterologist. Laboratory parameters at discharge: hemoglobin 91 g/L, red blood cells 3.3×1012/L.

Conclusion. The problem of gastrointestinal complications, including gastrointestinal bleeding in young children af-ter cardiac surgery, is extremely insufficiently covered in the scientific literature. Many questions remain unsolved re-garding the prevention, early diagnosis and treatment of bleeding, so research in this field remains relevant for both clinicians and scientists.

References

  1. Ferguson LP, GandiyaT, Kaselas C, Sheth J, Hasan A, Gabra HO. Gastrointestinal complications associated with the surgical treatment of heart disease in children. J Pediatr Surg. 2017;52(3):414-419. https://doi.org/10.1016/j.jpedsurg.2016.10.052
  2. Murni IK, Djer MM, Yanuarso PB, Putra ST, Advani N, Rachmat J, et al. Outcome of pediatric cardiac surgery and predictors of major complication in a developing country. Ann Pediatr Cardiol. 2019;12(1):38-44. https://doi.org/10.4103/apc.APC_146_17
  3. Ghanayem NS, Dearani JA, Welke KF, Béland MJ, Shen I, Ebels T. Gastrointestinal complications associated with the treatment of patients with congenital cardiac disease: consensus definitions from the Multi-Societal Database Committee for Pediatric and Congenital Heart Disease. Cardiol Young. 2008;18(Suppl. 2):240-244. https://doi.org/10.1017/S1047951108002989
  4. Allen SJ. Gastrointestinal Complications and Cardiac Surgery. J Extra Corpor Technol. 2014;46(2):142-149.
  5. Ng LQ, Choo JTL, Fortier MV, Chiou FK. Variceal Hemorrhage in Two Children With Congenital Heart Disease and Long-Term Pulmonary Venous Obstruction. JPGN Rep. 2020 Dec 3;2(1):e028. https://doi.org/10.1097/PG9.0000000000000028
  6. Fox VL. Gastrointestinal bleeding in infancy and childhood. Gastroenterol Clin North Am. 2000;29(1):37-66. https://doi.org/10.1016/s0889-8553(05)70107-2
  7. Aran AA, Karam O, Nellis ME. Bleeding in Critically Ill Children—Review of Literature, Knowledge Gaps, and Suggestions for Future Investigation. Front Pediatr. 2021 Jan 27;9:611680. https://doi.org/10.3389/fped.2021.611680
  8. Nellis ME, Tucci M, Lacroix J, Spinella PC, Haque KD, Stock A, et al.; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network; and the Pediatric Critical Care Blood Research Network (BloodNet). Bleeding Assessment Scale in Critically Ill Children (BASIC): Physician-Driven Diagnostic Criteria for Bleeding Severity. Crit Care Med. 2019;47(12):1766-1772. https://doi.org/10.1097/CCM.0000000000004025
  9. Owensby S, Taylor K, Wilkins T. Diagnosis and Management of Upper Gastrointestinal Bleeding in Children. J Am Board Fam Med. 2015;28(1):134-145. https://doi.org/10.3122/jabfm.2015.01.140153
  10. Lirio RA. Management of Upper Gastrointestinal Bleeding in Children: Variceal and Nonvariceal. Gastrointest Endosc Clin N Am. 2016;26(1):63-73. https://doi.org/10.1016/j.giec.2015.09.003
  11. Tringali A, Thomson M, Dumonceau JM, Tavares M, Tabbers MM, Furlano R, et al. Pediatric gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) and European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) Guideline Executive summary. Endoscopy. 2017;49(1):83-91. https://doi.org/10.1055/s-0042-111002
  12. Mills KI, Albert BD, Bechard LJ, Duggan CP, Kaza A, Rakoff-Nahoum S, et al. Stress ulcer prophylaxis versus placebo—a blinded randomized control trial to evaluate the safety of two strategies in critically ill infants with congenital heart disease (SUPPRESS-CHD). Trials. 2020 Jun 29;21(1):590. https://doi.org/10.1186/s13063-020-04513-w
  13. Abu El-Ella SS, El-Mekkawy MS, Mohamed Selim A. Stress ulcer prophylaxis for critically ill children: routine use needs to be re-examined. An Pediatr (Engl Ed). 2022;96(5):402-409. https://doi.org/10.1016/j.anpede.2021.03.001
Published
2023-09-28
How to Cite
1.
Tsymbal OI, Boyko SM. A Case of Duodenal Bleeding in a One-Year-Old Child in the Early Postoperative Period after the Surgical Correction of Congenital Heart Defect. ujcvs [Internet]. 2023Sep.28 [cited 2024Dec.22];31(3):139-42. Available from: https://cvs.org.ua/index.php/ujcvs/article/view/592