The First Local Experience of Use of Extracorporeal Circulatory Support with PROTEKDuo Dual-Lumen Cannula in a Patient with Acute Right Ventricular Failure

Keywords: pulmonary embolism, pulmonary thrombectomy, circulatory failure, high pulmonary resistance, right ventricular dysfunction, devices for mechanical support of circulation

Abstract

Acute right ventricular failure is a life-threatening condition that can occur as a result of a sudden increase in total pulmonary vascular resistance, in particular, as a result of pulmonary embolism. Most patients with thromboembolism are treated with thrombolytic therapy, but in some cases open thrombextraction is preferred. Removal of blood clots from the pulmonary vascular bed and cardiopulmonary bypass can lead to spasm of the pulmonary artery and to the elevation of total pulmonary resistance, which, in turn, increases the afterload on the right ventricle and can lead to a dramatic decrease in its mechanical function.

The aim. The aim of this report is to present the first experience of using the right ventricular bypass with the PROTEKDuo cannula for the purpose of temporary mechanical support of the right ventricle.

Case presentation. We studied a 63-year-old patient who underwent Studer technique for bladder adenocarcinoma. On the 14th day an acute massive pulmonary embolism occurred with a drop in hemodynamics and the presence of a floating clot on the right atrium. Thrombolysis carried significant risks due to possible bleeding and clot fragmentation in the right atrium with subsequent embolization of the pulmonary arteries. In these circumstances, open thrombectomy under hypothermic arrest was performed. Intraoperatively, the patient developed acute right ventricular failure resistant to all conservative therapy, therefore, right ventricular bypass was connected using PROTEKDuo, which made it possible to overcome the phenomena of acute right ventricular failure in the postoperative period.

Conclusions. Our experience with right ventricular bypass using the PROTEKDuo dual-lumen cannula demonstrates another useful option for saving patients with isolated right ventricular failure.

References

  1. Apostolakis S, Konstantinides S. The Right Ventricle in Health and Disease: Insights into Physiology, Pathophysiology and Diagnostic Management. Cardiology. 2012;121(4):263-273. https://doi.org/10.1159/000338705
  2. Walker LA, Buttrick PM. The Right Ventricle: Biologic Insights and Response to Disease: Updated. Curr Cardiol Rev. 2013;9(1):73-81. https://doi.org/10.2174/157340313805076296
  3. Fayad FH, Sellke FW, Feng J. Pulmonary hypertension associated with cardiopulmonary bypass and cardiac surgery. J Card Surg. 2022;37(12):5269-5287. https://doi.org/10.1111/jocs.17160
  4. Naveed A, Azam H, Murtaza HG, Ahmad RA, Baig MAR. Incidence and risk factors of Pulmonary Complications after Cardiopulmonary bypass. Pak J Med Sci. 2017 Jul-Aug;33(4):993-996. https://doi.org/10.12669/pjms.334.12846
  5. Lahm T, McCaslin CA, Wozniak TC, Ghumman W, Fadl YY, Obeidat OS, et al. Medical and Surgical Treatment of Acute Right Ventricular Failure. J Am Coll Cardiol. 2010;56(18):1435-1446. https://doi.org/10.1016/j.jacc.2010.05.046
  6. Skhiri M, Hunt SA, Denault AY, Haddad F. Evidence-Based Management of Right Heart Failure: a Systematic Review of an Empiric Field. Rev Esp Cardiol. 2010;63(4):451-471. https://doi.org/10.1016/S1885-5857(10)70094-3
  7. Aggarwal V, Einhorn BN, Cohen HA. Current status of percutaneous right ventricular assist devices: first-in-man use of novel dual lumen Cannula. Catheter Cardiovasc Interv. 2016;88(3):390-396. https://doi.org/10.1002/ccd.26348
  8. Kapur NK, Esposito ML, Bader Y, Morine KJ, Kiernan MS, Pham DT, et al. Mechanical Circulatory Support Devices for Acute Right Ventricular Failure. Circulation. 2017;136(3):314-326. https://doi.org/10.1161/CIRCULATIONAHA.116.025290
  9. Margey R, Chamakura S, Siddiqi S, Senapathi M, Schilling J, Fram D, et al. First experience with implantation of a percutaneous right ventricular Impella right side percutaneous support device as a bridge to recovery in acute right ventricular infarction complicated by cardiogenic shock in the United States. Circ Cardiovasc Interv. 2013;6(3):e37-e38. https://doi.org/10.1161/CIRCINTERVENTIONS.113.000283
Published
2023-06-26
How to Cite
1.
Dovgan OM, Paulouski ME, Honcharenko AI, Makedon AV, Prystaia YV. The First Local Experience of Use of Extracorporeal Circulatory Support with PROTEKDuo Dual-Lumen Cannula in a Patient with Acute Right Ventricular Failure. ujcvs [Internet]. 2023Jun.26 [cited 2024Dec.22];31(2):45-9. Available from: https://cvs.org.ua/index.php/ujcvs/article/view/563
Section
NEW TREATMENTS FOR CARDIOVASCULAR DISEASES