Transplantation of mononuclear cord stem cells at the refractory stage of heart failure
This work is based on analysis of heart failure (HF) natural history in 20 patients who underwent cord blood stem cell transplantation by intravenous rout. After this study we have registered a significant increase in exercise tolerance, improvement of life quality, reduction of heart failure signs and increase in the effectiveness of traditional schemes HF treatment.
2. Burkfoff D. New heart failure therapy:the shape of things to come? [Text] / D. Burkfoff // J Thorac Cardiovasc Surg. – 2001. – Vol. 122. – P. 421–423.
3. Marelli D., Desrosiers C., el-Alfy M., Kao R. L., Chiu R. C. Cell transplantation for myocardial repair: an experimental // Cell Transplant. – 1992. – Vol. 1. – P. 383–390.
4. Koh G. Y., Klug M. G., Soonpaa M. H., Field L. J. Differentiation and long-term survival of C2C12 myoblast graft in heart // J Clin Invest. – 1993. – Vol. 92: – P. 1548–1554.
5. Heart Failure Risk Calculator. Stuart J. Pocock // European Heart Journal. – 2012. – 1 (http://www.heartfailurerisk.org).