@article{Kravchuk_Maliarchuk_Paratsii_2016, title={Radiofrequency ablation in patients with left ventricular dysfunction induced by ventricular premature beats}, url={https://cvs.org.ua/index.php/ujcvs/article/view/242}, abstractNote={<p><strong>Aim of study</strong>: evaluation of left ventricular systolic function and its dependence on the number of VPB in patients with VPB-induced left ventricular dysfunction, which was treated by radiofrequency catheter ablation (RCA).</p> <p>In the analysis included 11 consecutive cases of patients with RCA of monomorphic VPB and LV dysfunction. The age of patients ranged from 18 to 46 years, including 7 (63%) women. The criterion of LV dysfunction was reduced LV ejection fraction (LVEF) below 50%. In all patients RCA of VPB’s substrate was performed by the standard method. The criterion for the efficiency of procedures was the number of VPB &lt;1% of the daily rhythm. Echocardiography was performed before the procedure and after 3 and 6 months; the daily monitoring of ECG was performed before the procedure, after 48 hours and after 6 months.</p> <p>RCA applications were performed in septal area of right ventricular outflow tract (RVOT) in 6 (54.5%) cases; RVOT free wall – in 3 (27.3%) patients and in 2 observations (18.2%) – in sinuses of Valsalva (p&lt;0.05). In one case in RVOT was early recurrence of VPB and RCA, which was effective, repeated after 1 week. All patients experienced a significant reduction in the number of VPB after ablation and after 48 hours and 6 months (p&lt;0,05). The number of VPB decreased from 34,415±6556,36 per day before ablation to 627,36±319,48 per day – 48 hours after ablation and 608,63±299,03 per day in 6 months after ablation. Percentage of VPB in the daily rhythm decreased from 33,62±6,06 before ablation to 0,6±0,32 48 hours after ablation and to 0,57±0,3 – 6 months after ablation, i.e. by 98%. LVEF increased from 43,82±3,19 before ablation to 54,27±4,47 after 6 months (p&lt;0,05). Directly proportional relationship between the percentage of VPB in the daily rhythm and LVEF (p&lt;0,05) was noted.</p> <p>In patients with VPB-induced LV dysfunction LVEF is in direct ratio to the percentage of VPB in a daily rhythm. RCA is effective method of treatment of VPB in patients with VPB-induced LV dysfunction, which enabled to reduce daily amount of VPB on 98% in the late period with reversion of LV dysfunction.</p&gt;}, number={2 (25)}, journal={Ukrainian Journal of Cardiovascular Surgery}, author={Kravchuk, B. and Maliarchuk, R. and Paratsii, O.}, year={2016}, month={Sep.}, pages={82-86} }