@article{Mykychak_Kozhokar_Yusifli_Yachnik_Zakharova_Yemets_2019, title={Relationship between Clinical Features and Histopathologic Findings in Patients with Pulmonary Vein Stenosis}, url={http://cvs.org.ua/index.php/ujcvs/article/view/118}, DOI={10.30702/ujcvs/19.3505/044061-063}, abstractNote={<p>Pulmonary vein stenosis (PVS) is a rare but serious condition characterized by obstruction of extrapulmonary segments of pulmonary veins which leads to progressive pulmonary hypertension.</p> <p><strong>Objective</strong>. In this study we aimed to determine relationship between clinical features and histopathologic findings in patients with PVS.</p> <p><strong>Material and methods</strong>. We retrospectively reviewed 34 consecutive patients who underwent PV stenosis repair. Surgical wedge biopsy specimens were collected intraoperatively in 11 patients and reviewed using light microscopy.</p> <p><strong>Results</strong>. Affected pulmonary veins in patients with primary PVS were characterized by diffuse stenosis extending into the lung parenchyma. In post-surgical group stenosis was found in a limited segment of pulmonary vein at its ostium. Microscopically, abnormal intimal proliferation was identified in both patient groups. Scaring was predominant finding in patients with post-surgical PVS.</p> <p><strong>Conclusion</strong>. In patients with PVS, pathophysiological mechanism influences the severity and extent of clinical manifestations. A comprehensive understanding of this mechanism may improve results of the treatment.</p&gt;}, number={2 (35)}, journal={Ukrainian Journal of Cardiovascular Surgery}, author={Mykychak, Y. and Kozhokar, D. and Yusifli, I. and Yachnik, O. and Zakharova, V. and Yemets, I.}, year={2019}, month={May}, pages={61-63} }